Published Aug 1990 by Marvel.
Part 1 of 5. Story, art and cover by Todd McFarlane. Fresh off his legendary run on Amazing Spider-Man, super-star artist Todd McFarlane is given the reigns to his very own Spidey title. Right out of the gate the wall-crawler will be challenged like never before as mysterious and ominous drums in the distance are driving the savage Lizard to cut a swath of death and destruction through the streets of New York City. Can Spider-Man discover the one responsible for this madness before his arch foe causes more damage?